Global News Post: Cancer

India: Software to Detect Breast Cancer

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</div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Trebuchet MS","sans-serif"; font-size: 12.0pt; line-height: 115%;">THIRUVANANTHAPURAM, India (NNN-Bernama) -- Researchers at the Cochin University of Science and Technology (CUSAT) in south Indian state Kerala have developed software that will help in accurate detection of breast cancer, Press Trust of India reported. <o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Trebuchet MS","sans-serif"; font-size: 12.0pt; line-height: 115%;">The automated software-based test will help the doctors analyse mammograms and detect micro-calcifications, the early indicators of breast cancer, with more perfection. <o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Trebuchet MS","sans-serif"; font-size: 12.0pt; line-height: 115%;">This will replace the existing manual method to detect the ailment. <o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Trebuchet MS","sans-serif"; font-size: 12.0pt; line-height: 115%;">CUSAT researchers claimed that the software can ensure a classification accuracy of 98 per cent and detection accuracy of 91.25 per cent. <o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Trebuchet MS","sans-serif"; font-size: 12.0pt; line-height: 115%;">The new research is also likely to bring down the input costs for majority of the health institutions, which could not afford the equipments, said Suma Mariam Jacob, a radiologist at a hospital in Kochi. <o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Trebuchet MS","sans-serif"; font-size: 12.0pt; line-height: 115%;">Only the state-run Regional Cancre Centre here has the fully digital mammography unit with computer-aided software detection for breast cancer. <o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Trebuchet MS","sans-serif"; font-size: 12.0pt; line-height: 115%;">Although agreeing that the development of the software would be a boon for breast cancer patients, Jacob said it should be brought through clinical trials before being put into usage. -- NNN-BERNAMA <o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><br />
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India: Software to Detect Breast Cancer

THIRUVANANTHAPURAM, India (NNN-Bernama) -- Researchers at the Cochin University of Science and Technology (CUSAT) in south Indian state K...

New Breast Cancer Treatment Shows Great Promise

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<div class="MsoNormal" style="text-align: justify;"><span style="background-color: white;"><span style="font-family: 'Trebuchet MS', sans-serif; font-size: xx-small;"><b>By Carol Pearson</b></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
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<tr><td class="tr-caption" style="text-align: center;"><div class="MsoNormal" style="font-size: medium;"><span class="apple-style-span"><span style="background-attachment: initial; background-clip: initial; background-color: white; background-image: initial; background-origin: initial; background-position: initial initial; background-repeat: initial initial;"><span style="font-family: 'Trebuchet MS', sans-serif;"><span style="font-size: xx-small;">In clinical trials at <st1:placename w:st="on">Johns</st1:placename> <st1:placename w:st="on">Hopkins</st1:placename> <st1:placename w:st="on">Cancer</st1:placename> <st1:placetype w:st="on">Center</st1:placetype> in <st1:place w:st="on"><st1:city w:st="on">Baltimore</st1:city>, <st1:state w:st="on">Maryland</st1:state></st1:place>, </span></span></span></span><span style="background-color: white; font-family: 'Trebuchet MS', sans-serif; font-size: xx-small;">doctors report </span></div><div class="MsoNormal" style="font-size: medium;"><span style="background-color: white; font-family: 'Trebuchet MS', sans-serif; font-size: xx-small;">they successfully pumped cancer-fighting medicine directly into a breast tumor. Photo: VOA News</span></div><div class="MsoNormal" style="font-size: medium; text-align: justify;"><br />
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</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">There's some promising news about breast cancer treatment. In clinical trials at  <st1:placename w:st="on">Johns</st1:placename> <st1:placename w:st="on">Hopkins</st1:placename> <st1:placename w:st="on">Cancer</st1:placename> <st1:placetype w:st="on">Center</st1:placetype> in <st1:place w:st="on"><st1:city w:st="on">Baltimore</st1:city>, <st1:state w:st="on">Maryland</st1:state></st1:place>, doctors report they successfully pumped cancer-fighting medicine directly into a breast tumor. Early results show the treatment not only kills the tumor, but spares the patients disfiguring surgery and the side effects of more radical treatments.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">The earliest stages of breast cancer are usually discovered during a mammogram. Right now, the standard treatment when tumors are found is surgery, followed by radiation therapy and then hormone treatment. Some women who have a high risk of getting breast cancer even opt to have mastectomies - the surgical removal of one or both breasts - just to reduce their risk.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">At <st1:placename w:st="on">Johns</st1:placename> <st1:placename w:st="on">Hopkins</st1:placename> <st1:placename w:st="on">Cancer</st1:placename> <st1:placetype w:st="on">Center</st1:placetype> in <st1:place w:st="on"><st1:city w:st="on">Baltimore</st1:city></st1:place>, one oncologist has been studying a less radical approach.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">"Since most cancers originate within the breasts and the cells that line the milk ducts within the breasts, can we possibly eliminate those dangerous cells, and by doing so, eliminate breast cancer?" asks Dr. Vared Sterns.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">The idea is simple. Give a small concentration of a chemotherapy drug directly through the patient's nipple and into the milk ducts where cancer cells or even pre-cancerous cells are forming. The entire procedure takes about 30 minutes. In clinical trials, researchers found this technique was more effective and less toxic than the conventional practice of administering chemotherapy through the vein.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">"What we found was that the concentration of the drug within the breast was very, very high, while the concentration of the drug within the blood system was very low," said Sterns.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">With conventional chemotherapy, the opposite was true: Drugs administered through the vein concentrated in the blood system and but were less concentrated where they were most needed - in the breast. The clinical trials have been so promising that this type of treatment might eventually become the standard for patients with very early stages of breast cancer or those who are at risk of developing it. <o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">"It is my hope that the treatment can be delivered in just your usual mammogram suite. This has been done in our study quite easily on an outpatient basis. It doesn't take very long. It's not painful," said Sterns.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">She likens this procedure to a colonoscopy. If there's a polyp, the doctor removes it before it can become cancerous.<o:p></o:p></span></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="background: white;"><span style="font-family: 'Trebuchet MS', sans-serif;">Dr. Sterns said researchers need to find out how much of the drug is needed and how often it should be administered to rid the breast of cancer. She estimates that work will take another 10 years. Then, if this procedure is as promising as it seems, it may become standard treatment for patients with early stage breast cancer. ---VOA News</span><o:p></o:p></span></span></div></div>

New Breast Cancer Treatment Shows Great Promise

By Carol Pearson In clinical trials at Johns Hopkins Cancer Center in Baltimore , Maryland , doctors report they successfull...

Vitamin E Linked to Higher Prostate Cancer Risk

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</span></div><div align="center" class="MsoNormal" style="text-align: center;"><span class="apple-style-span"><b><i><span style="color: black; font-family: "Trebuchet MS";">Effect lingers even after men stop taking popular supplement<o:p></o:p></span></i></b></span></div><div class="MsoNormal" style="text-align: justify;"><br />
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</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><b><i><span style="color: black; font-family: "Trebuchet MS"; font-size: 8.0pt;">By Rosanne Skirble from <st1:place w:st="on"><st1:city w:st="on">Washington</st1:city>, <st1:state w:st="on">D.C.</st1:state></st1:place><o:p></o:p></span></i></b></span></div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><b><i><span style="color: black; font-family: "Trebuchet MS"; font-size: 8.0pt;"><span>  </span><o:p></o:p></span></i></b></span></div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";"><span>  </span><o:p></o:p></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
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</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";">In 2001, scientists launched the Selenium and Vitamin E Cancer Prevention Trial (SELECT), to test the widely-held belief that the two supplements might help or prevent disease.<span>  </span>Analysis from studies on skin and lung cancers had suggested that the mineral supplement selenium or vitamin E might reduce the risk of prostate cancer.<span>    </span><o:p></o:p></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";">The study enrolled 35,000 healthy men, 50 years or older, at 400 sites in the <st1:country-region w:st="on">United  States</st1:country-region>, <st1:country-region w:st="on">Canada</st1:country-region> and <st1:place w:st="on">Puerto Rico</st1:place>. Eric Klein of the Cleveland Clinic says the $122 million dollar trial ended in 2008 when it became clear that it would not produce the 25 percent cancer reduction it was designed to show. <o:p></o:p></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
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</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";">“We did notice however at the time the original study was closed that men who were taking vitamin E alone were trending toward having a higher risk of prostate cancer.” <o:p></o:p></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";">Updated findings, reported in the Journal of the American Medical Association show, no benefit for men who took the 400 International units of vitamin E a day and more importantly, says co-author and National Cancer Institute prostate cancer expert Howard Parnes, a real risk. “At this time the data show a 17 percent increase in prostate cancer, which is statistically significant for the vitamin E alone.”<o:p></o:p></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";">Researchers followed post-study participants for 18 months after SELECT was halted. Klein, who also contributed to the article in the Journal of the American Medical Association, says the researchers found vitamin E can have an effect even after the men stopped taking the supplement.<o:p></o:p></span></span></div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";">“There just doesn’t seem to be a reason to be taking vitamin E if you are a man over 55 or 60.”<o:p></o:p></span></span></div><div class="MsoNormal" style="text-align: justify;"><br />
</div><div class="MsoNormal" style="text-align: justify;"><span class="apple-style-span"><span style="color: black; font-family: "Trebuchet MS";">Klein adds that the study underscores the importance of large-scale, population-based, randomized trials to accurately measure the benefit or harm of micronutrients such as diet supplements. ---VOA News</span></span></div></div>

Vitamin E Linked to Higher Prostate Cancer Risk

Effect lingers even after men stop taking popular supplement By Rosanne Skirble from Washington , D.C. In 2001, scientists launche...

'Serial Killer' Cells Demolish Leukemia Tumors

<div dir="ltr" style="text-align: left;" trbidi="on"><div dir="ltr" style="text-align: left;" trbidi="on"><div style="text-align: center;"><b><span class="Apple-style-span" style="color: red; font-family: 'Courier New', Courier, monospace; font-size: large;">Test patients show complete remission or significant improvement</span></b></div><br />
<span class="Apple-style-span" style="font-size: xx-small;"><b>By Jessica Berman from Washington, D.C.</b></span><br />
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<div style="text-align: justify;"><a href="http://www.amazon.com/Regulatory-Cells-Biology-Research-Progress/dp/1617615544?ie=UTF8&tag=glob036-20&link_code=bil&camp=213689&creative=392969" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;" target="_blank"><img alt="Regulatory T Cells (Cell Biology Research Progress: Immunology and Immune System Disorders)" height="320" src="http://ws.amazon.com/widgets/q?MarketPlace=US&ServiceVersion=20070822&ID=AsinImage&WS=1&Format=_SL160_&ASIN=1617615544&tag=glob036-20" width="212" /></a><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><img alt="" border="0" height="1" src="http://www.assoc-amazon.com/e/ir?t=glob036-20&l=bil&camp=213689&creative=392969&o=1&a=1617615544" style="border: none !important; margin: 0px !important; padding: 0px !important;" width="1" />U.S. researchers say they've been able to modify a patient's immune system T cells, turning them into “serial killer” cells which zero in on cancer and obliterate it.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">It’s being called a breakthrough in the treatment of a form of leukemia, a hard to treat and usually fatal blood cancer. </span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><a href="http://www.amazon.com/Medifocus-Guidebook-Chronic-Lymphocytic-Leukemia/dp/1453712348?ie=UTF8&tag=glob036-20&link_code=bil&camp=213689&creative=392969" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;" target="_blank"><img alt="Medifocus Guidebook on: Chronic Lymphocytic Leukemia" src="http://ws.amazon.com/widgets/q?MarketPlace=US&ServiceVersion=20070822&ID=AsinImage&WS=1&Format=_SL160_&ASIN=1453712348&tag=glob036-20" /></a><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><img alt="" border="0" height="1" src="http://www.assoc-amazon.com/e/ir?t=glob036-20&l=bil&camp=213689&creative=392969&o=1&a=1453712348" style="border: none !important; margin: 0px !important; padding: 0px !important;" width="1" />Chronic lymphocytic leukemia (CLL) is marked by a slow increase in immune system white blood cells, called B lymphocytes. These B cells, as they're known, are manufactured by the bone marrow, the spongy tissue inside bones that also manufactures red blood cells.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">Eventually, the healthy blood cells are crowded out by the proliferating B cells, the patient experiences bone marrow failure, and - without a bone marrow transplant - dies.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
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</span></div><div style="text-align: justify;"><a href="http://www.amazon.com/Bone-Marrow-Blood-Stem-Transplants/dp/0964735237?ie=UTF8&tag=glob036-20&link_code=bil&camp=213689&creative=392969" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;" target="_blank"><img alt="Bone Marrow and Blood Stem Cell Transplants: A Guide For Patients" src="http://ws.amazon.com/widgets/q?MarketPlace=US&ServiceVersion=20070822&ID=AsinImage&WS=1&Format=_SL160_&ASIN=0964735237&tag=glob036-20" /></a><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><img alt="" border="0" height="1" src="http://www.assoc-amazon.com/e/ir?t=glob036-20&l=bil&camp=213689&creative=392969&o=1&a=0964735237" style="border: none !important; margin: 0px !important; padding: 0px !important;" width="1" />A transplant of healthy bone marrow from a donor has been the only treatment and potential cure for chronic lymphocytic leukemia. But it is very difficult to find a match and many people with CLL die while waiting. Even with a transplant, experts say only about half of CLL patients survive the procedure.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">Three CLL patients who had run out of treatment options were selected for an experiment at the University of Pennsylvania. Researchers genetically engineered another one of their immune system cells, the T lymphocytes, to attack cancerous B cells.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><a href="http://www.amazon.com/Word-Book-Pathology-Laboratory-Medicine/dp/0721640400?ie=UTF8&tag=glob036-20&link_code=bil&camp=213689&creative=392969" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;" target="_blank"><img alt="Word Book in Pathology and Laboratory Medicine" src="http://ws.amazon.com/widgets/q?MarketPlace=US&ServiceVersion=20070822&ID=AsinImage&WS=1&Format=_SL160_&ASIN=0721640400&tag=glob036-20" /></a><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><img alt="" border="0" height="1" src="http://www.assoc-amazon.com/e/ir?t=glob036-20&l=bil&camp=213689&creative=392969&o=1&a=0721640400" style="border: none !important; margin: 0px !important; padding: 0px !important;" width="1" />Carl June, a professor of pathology and laboratory medicine at the school's Abramson Cancer Center, was the study's lead author. </span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">The actual trial exceeded our wildest outcome and imagination actually," says Carl June, professor of pathology and laboratory medicine, who was the study’s lead author, "because what we found is all three patients have had a remarkable anti-tumor response and that literally pounds of leukemia have been eradicated in all three patients.”</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">Two of the three CLL patients had a complete remission of their disease and there was a significant improvement in the third.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
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</span></div><div style="text-align: center;"><div style="text-align: left;"><span class="Apple-style-span" style="color: #cc0000; font-family: 'Courier New', Courier, monospace;"><b>Watch related video story by Vidushi Sinha</b></span></div></div><div style="text-align: justify;"><div style="text-align: left;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><object data="http://serve.a-widget.com/service/getWidgetSwf.kickAction" height="300" id="kickWidget_45137_301823" name="kickWidget_45137_301823" type="application/x-shockwave-flash" width="480">     <param name="movie" value="http://serve.a-widget.com/service/getWidgetSwf.kickAction"></param><param name="FlashVars" value="affiliateSiteId=45137&widgetId=301823&width=480&height=300&revision=178&playOnLoad=0&mediaType_mediaID=video_1619917&autoPlay=0&varsToAppendToLinks=http%3A%2F%2Faffiliate.kickapps.com%2Fservice%2FgetFeed.kickAction%3FmediaId%3D1619917%26mediaType%3Dvideo%26as%3D45137" ></param><param name="wmode" value="transparent" ></param><param name="allowFullScreen" value="true" ></param><param name="allowScriptAccess" value="always" ></param></object></span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
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</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">The T cells were genetically modified using a harmless virus, which carried an anti-body called a chimeric antigen receptor (CAR). Antibodies are immune system proteins which are produced in response to an infection. </span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">The CAR was engineered to bind to another protein called CD19 that’s present on the surface of normal B lymphocytes and all CLL tumor cells. </span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">Scientists say the modified T cells, injected into the patients following standard chemotherapy, homed in on the cancerous B cells inside the bone marrow, each T lymphocyte killing thousands of tumor cells. </span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">Researcher Michael Kalos says the team also engineered a signaling molecule that binds to CD19, triggering the continued production of thousands of T cells. The genetically engineered cells act as sentries against cancerous B cells should they return.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">We saw a substantial number of cells remaining circulating and in the marrow of patients very, very late after infusion, nine to 12 months, entirely unprecedented in the field," says Kalos. "And finally we saw that those cells, not only did they remain there, but they were able to be triggered, recognize and kill cancer cells when they encountered them again.”</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">In a report describing the so-called “serial killer” T cell therapy in the New England Journal of Medicine, researchers say it completely obliterated cancer cells in a 64-year-old man with CLL three weeks after treatment, and three to six months later, researchers could detect no sign of disease.</span></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;">The patient’s marrow began manufacturing healthy B cells to replace the ones that were destroyed as "collateral damage" by the therapy. Cells that did not express CD19 were unaffected. (VOA News)</span></div></div><div style="text-align: justify;"><span class="Apple-style-span" style="font-family: 'Courier New', Courier, monospace; font-size: large;"><br />
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'Serial Killer' Cells Demolish Leukemia Tumors

Test patients show complete remission or significant improvement By Jessica Berman from Washington, D.C. U.S. researchers say they'v...

British Doctors Successfully Test Cancer Vaccine in Mice

<div dir="ltr" style="text-align: left;" trbidi="on"><br />
<div class="MsoNormal" style="text-align: justify;"><span class="Apple-style-span" style="font-family: Arial, sans-serif;"><span class="Apple-style-span" style="line-height: 18px;"><br />
</span></span></div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Arial","sans-serif"; font-size: 12.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-weight: bold; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;">British researchers say they have developed a vaccine that appears to cure prostate cancer in mice. The vaccine works by triggering the body's own immune system to attack cancer cells while leaving healthy cells alone.<o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Arial","sans-serif"; font-size: 12.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-weight: bold; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;"><br />
</span></div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Arial","sans-serif"; font-size: 12.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-weight: bold; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;">The scientists, writing in the journal Nature Medicine, developed a special vaccine using the genetic code from a healthy human prostate which they inserted into a virus. When the virus was injected into cancer-ridden mice, it triggered the immune system not only to fight off the virus but also to attack the cancer cells.<o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Arial","sans-serif"; font-size: 12.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-weight: bold; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;"><br />
</span></div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Arial","sans-serif"; font-size: 12.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-weight: bold; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;">Researchers have for years tried to produce a cancer vaccine that works like this one and they say it could work for a range of other cancers.<o:p></o:p></span></div><div class="MsoNormal" style="text-align: justify;"><span style="font-family: "Arial","sans-serif"; font-size: 12.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-weight: bold; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;">While encouraged by the results in the mice, the scientists say more research is needed, and it may be years before an effective cancer vaccine is ready for humans. </span><b><i style="mso-bidi-font-style: normal;"><span style="font-family: "Arial","sans-serif"; font-size: 7.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-size: 12.0pt; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;">(VOA News)</span></i></b><span style="font-family: "Arial","sans-serif"; font-size: 12.0pt; line-height: 115%; mso-ascii-theme-font: major-latin; mso-bidi-font-weight: bold; mso-bidi-language: AR-SA; mso-bidi-theme-font: major-latin; mso-fareast-font-family: "Times New Roman"; mso-hansi-theme-font: major-latin;"><o:p></o:p></span></div></div>

British Doctors Successfully Test Cancer Vaccine in Mice

British researchers say they have developed a vaccine that appears to cure prostate cancer in mice. The vaccine works by triggering the bo...